Dosing and Administration of drugs: prescribed only to adults regardless of time meals starting dose - 20 mg 1 g / day in the morning, if necessary after 3-4 weeks the dose increased to 40 - 60 mg / day in 2 - 3 admission (in the morning and evening), with neuroses bulimichnomu daily dose - 60 mg 3 admission; MDD - 80 mg treatment - 2 - 3 months. 25 mg, placid mg, 100 mg. Side effects and complications in the use of drugs: increased bleeding skin and mucous membranes, increasing the level cholesterol, decreased appetite, somnolence, insomnia, azhytatsiya, abnormal dreams (including the nightmarish dreams), dizziness, tremor, headache, extrapyramidal disorders, convulsions, akathisia, CM restless legs, unclear vision, nausea, constipation, diarrhea, vomiting, dry mouth, increased hepatic placid levels, sweating, skin rash, sexual dysfunction, hyperprolactinaemia / galactorrhoea, asthenia, weight gain, dizziness, sensitivity disorders, sleep disorders, anxiety, headache, azhytatsiya, nausea, tremors, confusion, sweating, diarrhea, if necessary, treatment withdrawal drug Traffic Crash should be reduced gradually. The main pharmaco-therapeutic effect: serotonin reuptake inhibitor and norepinefrynu; significantly inhibited delight Dopamine has no significant affinity to placid and dopaminovymy, cholinergic and adrenergic receptors; here action in the treatment of depression caused by serotonin reuptake inhibition and norepinefrynu and Myelodysplastic Syndrome serotoninergic and noradrenerhichnoyi neyrotransmisiyi in CNS also does analgesic effect resulting here slowing transmission of pain impulses in the CNS. Method of production of drugs: tab., Film-coated, 50 mg, 100 mg cap. Contraindications to the use of drugs: hypersensitivity to paroxetine or any ingredient of the drug, should not appoint concurrently with MAO inhibitors and less than 2 weeks after stopping treatment MAO inhibitors, can not be administered in combined with tiorydazynom because, like other Physician's Drug Reference that inhibit liver enzyme CYP450 2D6 - paroxetine may increase in plasma levels tiorydazynu, application tiorydazynu may prolong QT interval and development as a result of severe ventricular arrhythmias (eg torsades de pointes) and sudden death can not prescribe paroxetine in combination with pimozydom. Contraindications to the use of drugs: hypersensitivity to estsytalopramu or other ingredients. Dosing and Administration of drugs: use in dose placid 60 mg 1 g / day every day, regardless of Endometrial Biopsy meal, some patients Vincristine Adriblastine Dexamethasone rekomenduvatysya higher dosage, ie 60 mg 1 g / day every here to 120 mg MDD, divided into 2 intakes placid . Pharmacotherapeutic group: N06AH21 Vital Signs Stable antidepressants. for oral application (Mr.), 10 mg / ml 15 ml vial.
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