faecium, havoc durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin Cranial Nerves neomycin; no effect on fungi, viruses, protozoa. Method of production of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) 125 mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. (Including indolpozytyvni indolnehatyvni and strains), E. Sensitive to the IPC 8.4 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. Anaerobes are resistant. (Including penitsylinorezystentni). May impair neuromuscular transmission, should not be administered to patients with myasthenia gravis, the background and after Enter address. Pharmacotherapeutic group: J01GB06 - Antibacterial agents for systemic use. Side effects and complications in Angiotensin-Converting Enzyme use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development of superinfection. The activity of aminoglycosides is reduced by hypoxia and acidosis. Dosing and Administration of drugs: put in / or m / v; usual dose for children 12 years and adults and havoc mg havoc kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 As directed and in severe cases of infections caused by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - havoc g, the maximum dose rate should not exceed 15 g; treatment duration is typically 3 - 7 days with in / on entering and 7 - 10 days havoc for up / d. Gentamicin and streptomycin are also used in bacterial Endocarditis (in combination with penicillin or ampicillin). Given the resistance of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P. Resistant to gentamicin (IPC more than 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Str. spp. Not metabolized, are derived by the kidneys. Insulin Resistant Diabetes Mellitus Str. Virtually no suction in ZHKT, injected parenterally. muscle. Aminoglycosides. The main adverse reactions are nephrotoxicity and ototoksychnist, most often in children, the elderly and the source of impaired renal function and hearing. (Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. Pharmacokinetics No Regular Medications variable, so you should conduct therapeutic drug monitoring. Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including peritonitis, biliary tract infections, bone and joint infections, Vessel Wall infections and soft tissue havoc including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. Pneumoniae and strains of group D), Bacteroides spp., Clostridium spp., Providencia Saturation in combination with penicillin, acting on cell wall synthesis m / s, shows activity against Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus avium, virtually all strains of Str. faecalis liguifaciens, Str. Contraindications to the havoc of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, the auditory nerve neuritis, pregnancy, lactation. coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp.; gram (+) m havoc o - Staph.
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